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Do bone mineral content and density determine fracture in children? A possible threshold for physical activity. / Martins, Ana; Monjardino, Teresa; Nogueira, Luísa; Canhão, Helena; Lucas, Raquel.

Vol. 82, No. 3, 01.09.2017, p. 396-404.

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Martins A, Monjardino T, Nogueira L, Canhão H, Lucas R. Do bone mineral content and density determine fracture in children? A possible threshold for physical activity. 2017 Sep 1;82(3):396-404. Available from, DOI: 10.1038/pr.2017.113

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Martins, Ana; Monjardino, Teresa; Nogueira, Luísa; Canhão, Helena; Lucas, Raquel / Do bone mineral content and density determine fracture in children? A possible threshold for physical activity.

Vol. 82, No. 3, 01.09.2017, p. 396-404.

Research output: Contribution to journalArticle

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@article{85094a6f022948fb9118ebd712987a35,
title = "Do bone mineral content and density determine fracture in children? A possible threshold for physical activity",
abstract = "BackgroundRelations between bone parameters, physical exertion, and childhood fractures are complex. We aimed to estimate the associations between fracture history and bone mineral content (BMC) and areal bone mineral density (aBMD) at 7 years of age, by levels of physical activity, as a proxy for trauma frequency.MethodsWe used data collected from 2,261 children of the Generation XXI birth cohort, assembled in 2005/6 in Porto, Portugal. At the age of 7 years (2012/4), fracture history, time spent per week in active play, and sports practice were reported by parents. Subtotal and lumbar spine (LS) BMC and aBMD were measured using whole-body dual-energy X-ray absorptiometry.ResultsBoys and girls in the highest categories of time spent in sports practice or active play generally had higher BMC and aBMD. Among girls, BMC and aBMD were protective of fracture only in the highest quarter of active play (>660 min/week) - odds ratios (OR; 95% confidence interval (95% CI)) for subtotal BMC=0.27 (0.11-0.67), subtotal aBMD=0.18 (0.06-0.49), and LS aBMD=0.41 (0.22-0.75). For boys in the highest quarter of sports practice (>240 min/week), subtotal and LS BMC were protective of fracture - OR=0.39 (0.16-0.98) and 0.51 (0.27-0.96), respectively.ConclusionIn prepubertal children, BMC and aBMD predicted fracture history only in the highest levels of physical activity.",
author = "Ana Martins and Teresa Monjardino and Luísa Nogueira and Helena Canhão and Raquel Lucas",
year = "2017",
month = "9",
doi = "10.1038/pr.2017.113",
volume = "82",
pages = "396--404",
number = "3",

}

RIS

TY - JOUR

T1 - Do bone mineral content and density determine fracture in children? A possible threshold for physical activity

AU - Martins,Ana

AU - Monjardino,Teresa

AU - Nogueira,Luísa

AU - Canhão,Helena

AU - Lucas,Raquel

PY - 2017/9/1

Y1 - 2017/9/1

N2 - BackgroundRelations between bone parameters, physical exertion, and childhood fractures are complex. We aimed to estimate the associations between fracture history and bone mineral content (BMC) and areal bone mineral density (aBMD) at 7 years of age, by levels of physical activity, as a proxy for trauma frequency.MethodsWe used data collected from 2,261 children of the Generation XXI birth cohort, assembled in 2005/6 in Porto, Portugal. At the age of 7 years (2012/4), fracture history, time spent per week in active play, and sports practice were reported by parents. Subtotal and lumbar spine (LS) BMC and aBMD were measured using whole-body dual-energy X-ray absorptiometry.ResultsBoys and girls in the highest categories of time spent in sports practice or active play generally had higher BMC and aBMD. Among girls, BMC and aBMD were protective of fracture only in the highest quarter of active play (>660 min/week) - odds ratios (OR; 95% confidence interval (95% CI)) for subtotal BMC=0.27 (0.11-0.67), subtotal aBMD=0.18 (0.06-0.49), and LS aBMD=0.41 (0.22-0.75). For boys in the highest quarter of sports practice (>240 min/week), subtotal and LS BMC were protective of fracture - OR=0.39 (0.16-0.98) and 0.51 (0.27-0.96), respectively.ConclusionIn prepubertal children, BMC and aBMD predicted fracture history only in the highest levels of physical activity.

AB - BackgroundRelations between bone parameters, physical exertion, and childhood fractures are complex. We aimed to estimate the associations between fracture history and bone mineral content (BMC) and areal bone mineral density (aBMD) at 7 years of age, by levels of physical activity, as a proxy for trauma frequency.MethodsWe used data collected from 2,261 children of the Generation XXI birth cohort, assembled in 2005/6 in Porto, Portugal. At the age of 7 years (2012/4), fracture history, time spent per week in active play, and sports practice were reported by parents. Subtotal and lumbar spine (LS) BMC and aBMD were measured using whole-body dual-energy X-ray absorptiometry.ResultsBoys and girls in the highest categories of time spent in sports practice or active play generally had higher BMC and aBMD. Among girls, BMC and aBMD were protective of fracture only in the highest quarter of active play (>660 min/week) - odds ratios (OR; 95% confidence interval (95% CI)) for subtotal BMC=0.27 (0.11-0.67), subtotal aBMD=0.18 (0.06-0.49), and LS aBMD=0.41 (0.22-0.75). For boys in the highest quarter of sports practice (>240 min/week), subtotal and LS BMC were protective of fracture - OR=0.39 (0.16-0.98) and 0.51 (0.27-0.96), respectively.ConclusionIn prepubertal children, BMC and aBMD predicted fracture history only in the highest levels of physical activity.

UR - http://www.scopus.com/inward/record.url?scp=85021872455&partnerID=8YFLogxK

U2 - 10.1038/pr.2017.113

DO - 10.1038/pr.2017.113

M3 - Article

VL - 82

SP - 396

EP - 404

IS - 3

ER -

ID: 3094397